The Scarlets believe they can be successful in the away outing, with plans to avenge their 22 16 loss at Parc Y Scarlets.
"It's something that good players can adapt to. The Heineken Cup is a learning experience for us and this is just a different one."
It's another critical clash for the Chiefs, who follow this weekend with a trip to unbeaten pool leaders Clermont Auvergne before hosting defending champions Leinster.
The Chiefs, desperate to progress in the competition, make a few changes to their starting Under Armour Camo Shoes XV. Into the fold are Aly Muldowney, James Hanks and Dean Mumm. Ian Whitten, Jack Nowell and Phil Dollman are also given the nod.
Replacements: 16 Neil Clark, 17 Ben Moon, 18 Carl Rimmer, 19 Damian Welch, 20 Ben White, 21 Kevin Barrett, 22 Ignacio Mieres, 23 Luke Arscott.
Also featuring will be England international Tom Johnson, who is set to make his 150th appearance for the club.
The Scarlets welcome back Welsh international George North, centre Jonathan Davies captains his side once more and Ken Owens starts at hooker. South African signing George Earle moves to the back row for the injured Aaron Shingler.
Easterby"It is vital we get back momentum. We're obviously frustrated and disappointed with our three results in the Heineken Cup.
Scarlets will need to find the form that had seen them win five straight in competitive matches to re establish any hopes of progressing.
Russia Rugby World Cup News
Scarlets 15 Liam Williams, 14 George North, 13 Jonathan Davies (capt), 12 Scott Williams, 11 Gareth Maule, 10 Aled Thomas, 9 Aled Davies, 8 Kieran Murphy, 7 Johnathan Edwards, 6 George Earle, 5 Richard Kelly, Under Armour Curry Basketball Shoes
4 Sione Timani, 3 Samson Lee, 2 Ken Owens, 1 Shaun Hopkins.
"The opportunity now rests with us to turn it around with a big result this weekend. We've been good on the road this year and it's certainly not beyond us to get a result there."
Scarlets head coach Simon Under Armour Clutchfit Drive Low 3
6 Dean Mumm, 5 James Hanks, 4 Aly Muldowney, 3 Hoani Tui, 2 Simon Alcott, 1 Brett Sturgess.
Exeter: 15 Phil Dollman, 14 Jack Nowell, 13 Sireli Naqelevuki, 12 Ian Whitten, 11 Gonzalo Camacho, 10 Gareth Steenson, 9 Haydn Thomas, 8 Tom Johnson, 7 James Scaysbrook (capt), Under Armour Gemini Black
Nike Lebron 11 Price
Under Armour Shoes Tactical
Under Armour Shoes Blue And Orange
Under Armour Drive Highlight 1.5
Nike Lebron 12 Nsw Lifestyle Denim
Nike Metcon 1 Volt Grey
Under Armour Black And White Shoes
Under Armour Training Shoes
Nike Metcon Flyknit 3
Under Armour Mens Shoes Blue
Under Armour Shoes Stephen Curry Blue
Under Armour White Shoes
Nike Metcon 3 Dsx Flyknit - Men's
Under Armour Micro G Training Shoes
Under Armour Clutchfit 4