"This funding announcement couldn't come at a more exciting time in this field," Linhardt said in a statement. "We are exceptionally fortunate to conduct our research in a state that shows strong support for stem cell research. New York's initiative will allow us to jump off the blocks well before researchers in other states."
the brain. Progressive bone shortening is also a risk factor with the mutation, which occurs through a process known as skeletal chondrodysplasias. Through the examination of mouse bone and neural stem cells, the team will attempt to pinpoint the affect of an alteration or removal of the filamin and formin genes.
Robert Linhardt, the Ann and John H. Broadbent Jr. '59 Senior Constellation professor of Biocatalysis and Metabolic Engineering, and Russell Ferland, assistant professor of biology, will partner with groups from other universities to explore the development and mutation of stem cells.
"One of the main hurdles to the use of the stem cells in therapeutic applications is that has proven very difficult Under Armour Shoes Women to control the state of the cells once they are implanted," Linhardt said. "We want the stem cells to perform the function lost, but we do not want them to become cancerous."
Linhardt and his team will be examining a sugary coating on human stem cells called the glyco niche, one aspect of a larger environment that surrounds each stem cell. Current research indicates that the glyco niche could be a major factor in controlling cancerous cells. The grant will allow Linhardt to analyze growing human embryonic stem cells and track the changes of the glyco niche during the maturation process through the use of new technologies developed in the Dordick lab.
RPI teams to get grants for stem cell research
Ferland will work with Volney Sheen at Harvard Medical School to examine how specific genes dictate the function of stem cells, specifically the filamin and formin genes. Mutation of these genes, which affect brain and Under Armour Shoes Micro G
The grants will allow the two groups to discover new insights into the relationship between stem cell function and specific biological molecules and genes found in the human body.
experimental approach gives us the advantage of not only beginning to understand the role of these genes in stem cell function, but also for gaining greater insight in understanding these diseases," Ferland said.
A pair of Rensselaer Polytechnic Institute research groups has been awarded $1.08 million in grants through New York State's stem cell research initiative.
Linhardt will be work alongside a number of researchers from the University of Georgia, as well as Jonathan Dordick, the Howard P. Isermann '42 Professor of Chemical and Biological Engineering and director of the university's Center for Biotechnology and Interdisciplinary Studies.
bone stem cells, can lead to periventricular heterotopia, which can cause nodules to form in the neurons on Under Armour Micro G Sting
The Institutional Stem Cell Research Organization will review all research occurring at RPI to ensure safe and ethical research in accordance with state and federal guidelines.
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